Hart G.W. Lidov

This study reduces FMR1 expression in human cortical slices to model Fragile X syndrome, revealing cell type-specific transcriptomic and electrophysiological changes not observed in mouse models.

This study identifies disrupted O-GalNAc glycosylation as a mechanism and biomarker for SLC35A2-associated epilepsy using mouse models and human tissue analysis.

This paper demonstrates that modified self-amplifying RNA (saRNA) enables long-lasting protein expression in mouse and human brain tissues.

The paper identifies a novel fibroblast subtype in the choroid plexus that forms a barrier between the choroid plexus stroma, brain, and cerebrospinal fluid.

The paper shows the ChP acts as an immune organ in brain inflammation, with immune cell interactions and epithelial cell specialization regulating the barrier.