Nicole Briceno

This study identifies Gpr149 as an endogenous antigen in SB28 glioblastoma that can be targeted by vaccination to induce protective immunity against checkpoint inhibitor-refractory tumors.

This study identifies HexBMP(22:6_22:6) as a novel biomarker for mutant GBA1 using lysosomal profiling in mice and human samples.

This study shows that viral vector vaccination induces brain-resident memory T cells that effectively combat glioblastoma, offering a potential therapeutic strategy.

This study shows that altering sphingosine levels in IDH1mut glioma cells disrupts cholesterol homeostasis, leading to apoptosis through effects on cholesterol synthesis, uptake, and efflux.

The paper identifies Parkinson's risk variants in a SNCA enhancer by analyzing open chromatin in mouse dopamine neurons and validates their function in zebrafish and mice.