Yen‐Chun Ho

A regenerative fibroblast competence field supports multiple cell fates in adult skin regeneration

This study identifies NCAM1 as a regulator of regenerative competence in adult skin wounds through single-cell RNA sequencing and functional analysis.

Hyperglycemia-Driven Hepatic Immune Dysfunction Facilitates Microbial Dissemination Post-Myocardial Infarction

This study investigates how hyperglycemia worsens gut barrier disruption and liver immune dysfunction after myocardial infarction, leading to increased microbial dissemination and systemic inflammation.

S1PR1 Regulates Lymphatic Valve Development And Prevents Ileitis-Independent Tertiary Lymphoid Organ Formation

This study shows that S1PR1 regulates lymphatic valve development and prevents tertiary lymphoid organ formation in the terminal ileum, suggesting TLOs as a sign of subclinical inflammation.

PROX1 inhibits PDGF-B expression to prevent myxomatous degeneration of heart valves

This paper shows that PROX1 inhibits PDGF-B expression in heart valves to prevent myxomatous degeneration, and PDGF-B inhibition ameliorates valve defects in mice.

S1PR1 regulates the quiescence of lymphatic vessels by inhibiting laminar shear stress-dependent VEGF-C signaling

This study identifies S1PR1 as a regulator of lymphatic vessel quiescence by inhibiting LSS-dependent VEGF-C signaling in lymphatic endothelial cells.

GATA2 controls lymphatic endothelial cell junctional integrity and lymphovenous valve morphogenesis through miR-126

This study identifies GATA2's role in maintaining lymphatic endothelial cell junctions and valve morphogenesis through regulation of miR-126.