Author

Irıs D. Nagtegaal

Radboud University Medical CenterORCID 0000-0003-0887-4127Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Ana Krotenberg GarcíaiD· 1 shared Antoine KhaliliD· 1 shared Carlos Perez GonzaleziD· 1 shared Danijela Matic VignjeviciD· 1 shared Esther Strating· 1 shared Femke SimmeriD· 1 shared Hugo J.G. SnippertiD· 1 shared Jacco van RheeneniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Ana Krotenberg GarcíaORCID

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1 paper

Recent·Most cited

Cancer BiologyCell ReportsPeer-reviewedSep 23, 2025

Mechanical regulation of cell fate transitions underlying colorectal cancer metastasis formation

Mirjam C. van der Net, Marjolein J. Vliem, Lars J S Kemp…·Martijn Gloerich

This study shows that mechanical signals from the Collagen I-rich matrix drive fate transitions in colorectal cancer cells, enabling metastasis despite lacking Lgr5 expression.

17 citationstop 5%

humanbulk RNA-seq

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