Author
The Netherlands Cancer InstituteORCID 0000-0001-8175-1647Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Sonja D. C. Weterings, Hiromune Eto, Jan-Daniël de Leede-Scheven…·Katharina F. Sonnen
The paper shows that NOTCH-driven Hes1 oscillations with different periods control cell fate decisions in intestinal stem cells, influencing secretory and absorptive lineage commitment.
Thijs Makaske, Vincent J. W. Hellebrekers, Albert K. Serweta…·Lukas C. Kapitein
This study uses expansion microscopy to analyze three-dimensional ultrastructure of intestinal tissues and organoids, revealing disease-specific phenotypes in a microvillus inclusion disease model.
Carlos Perez Gonzalez, David B. Brückner, Mickaël Di‐Luoffo…·Danijela Matic Vignjevic
This study shows cancer cells follow intrinsic self-organized programs that coordinate tumor cell state transitions during growth, revealing mechanical gradients and stereotyped patterns of heterogeneity and plasticity.
Julian R. Buissant des Amorie, Max A. Betjes, Jochem H. Bernink…·Hugo J.G. Snippert
The paper identifies sequential transcriptomic states of tuft cells along the intestinal crypt-villus axis and shows cytokine-specific differentiation into distinct tuft cell phenotypes.
Daniel Postrach, Colin E.J. Pritchard, Larissa Frank…·Hans-Reimer Rodewald
Polytope enables high-resolution spatial fate-mapping by generating unique color codes through epitope barcoding in vivo.
Ignasi Granero-Moya, Valeria Venturini, Guillaume Belthier…·Pere Roca‐Cusachs
The paper shows that nucleocytoplasmic transport (NCT) in cell monolayers responds to mechanical forces but not cell density, contrasting with YAP's response to both mechanics and cell density.