Joel A. Swanson

This study identifies VPS34 complex II as a regulator of macropinocytosis through PI(3)P signaling, showing its distinct role from class I PI3K activity.

This study shows HIV-1 gp120 triggers macropinocytosis in CD4+ T cells, which facilitates HIV-1 infection through a calcium-independent phospholipase A2-dependent pathway.

This study shows HIV-1 enters primary CD4+ T cells via macropinocytosis, a process that can be inhibited to block viral entry and infection.

This study shows that murine macrophages under CSF1 stimulation rely on pinocytosis for solute influx and growth, with leucine affecting both protein synthesis and solute accumulation.