Jamil Zola Kitoko

This study shows that age-related decline in adipose tissue lipolysis reduces disease tolerance to SARS-CoV-2, increasing mortality in older mice and correlating with human COVID-19 severity.

This study identifies two anti-ferroptosis pathways in iron-recycling macrophages that prevent cell death and maintain iron homeostasis, revealing a key role for ferroptosis in iron deficiency anemia.

The paper identifies unconjugated bilirubin as a protective metabolite against malaria by inhibiting parasite proliferation and hemozoin formation.

This study identifies adipocyte lipolysis as a critical metabolic process that prevents sepsis in mice by supporting energy metabolism and thermoregulation through insulin signaling, without affecting bacterial burden.

The paper shows that Mif-/- mice host a pathogenic microbiota that causes lethal disease in Il10-/- mice, revealing a mechanism of disease tolerance through microbiota transfer.