Author

Marnix H. P. de Groot

The Netherlands Cancer InstituteORCID 0000-0003-1013-868XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Ben MorrisiD· 1 shared Camiel GöbeliD· 1 shared Daan J. KloostermaniD· 1 shared Daniël de Groot· 1 shared Eirini Kasa· 1 shared Fred van LeeuweniD· 1 shared Heinz JacobsiD· 1 shared Jayashree JayachandraniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Ben MorrisORCID

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1 paper

Recent·Most cited

Cancer BiologyBloodPeer-reviewedJan 10, 2025

Targeting DOT1L and EZH2 synergizes in breaking the germinal center identity of Diffuse Large B Cell Lymphoma

Camiel Göbel, Rachele Niccolai, Marnix H. P. de Groot…·Heinz Jacobs

This study shows that targeting DOT1L and EZH2 together disrupts the germinal center identity of GCB-DLBCL cells, leading to a cell-identity crisis and reduced tumor growth in vivo.

18 citationstop 1%

humanChIP-seq

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