Author

Daan J. Kloosterman

Oncode InstituteORCID 0000-0003-1082-070XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Ali ErtürkiD· 1 shared Amber K. L. WezenaariD· 1 shared Anna AlemanyiD· 1 shared Anne C. RiosiD· 1 shared Annelisa M. CorneliD· 1 shared Annette KünkeleiD· 1 shared Ben MorrisiD· 1 shared Camiel GöbeliD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

Ali ErtürkORCID

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2 papers

Recent·Most cited

Cancer BiologyNature CancerPeer-reviewedJan 5, 2026

De novo H3.3K27M-altered Diffuse Midline Glioma in human brainstem organoids to dissect GD2 CAR T cell function

Nils Bessler, Amber K. L. Wezenaar, Hendrikus CR Ariese…·Anne C. Rios

This paper develops a human brainstem organoid model of H3.3K27M-altered DMG to study GD2 CAR T cell function and identify therapeutic targets.

15 citationstop 1%

humanorganoid / primary culture

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Cancer BiologyBloodPeer-reviewedJan 10, 2025

Targeting DOT1L and EZH2 synergizes in breaking the germinal center identity of Diffuse Large B Cell Lymphoma

Camiel Göbel, Rachele Niccolai, Marnix H. P. de Groot…·Heinz Jacobs

This study shows that targeting DOT1L and EZH2 together disrupts the germinal center identity of GCB-DLBCL cells, leading to a cell-identity crisis and reduced tumor growth in vivo.

18 citationstop 1%

𝕏 PostBluesky