Guoliang Yin

Chaperonin TRiC bridges radial spokes for folding proteins locally translated in mammalian sperm flagella

The paper identifies TRiC/CCT as a chaperonin in mammalian sperm flagella that folds locally translated proteins, supporting flagellar function and fertility.

Essential role of CFAP77-CCDC105-TEX43 subcomplex in connecting axonemal A and B tubules for mammalian sperm motility

This study shows that CFAP77 is essential for connecting axonemal A and B tubules in mammalian sperm, as its loss disrupts the CFAP77-CCDC105-TEX43 complex and impairs sperm motility.

ANKRD5: a key component of the axoneme required for spermmotility and male fertility

This study identifies ANKRD5 as a critical component of the N-DRC in sperm axonemes, showing its role in maintaining structural integrity and motility, with implications for male fertility.

In-cell structural insight into the asymmetric assembly of central apparatus in mammalian sperm axoneme

The paper solves the in-cell structure of mouse sperm central apparatus at sub-nanometer resolution and identifies proteins critical for its asymmetric assembly.

Determining the architecture of nuclear ring of Xenopus laevis nuclear pore complex using integrated approaches

The paper determines the architecture of the nuclear ring in Xenopus laevis NPC using cryo-EM, homology modeling, and cell experiments, identifying key proteins and their roles in NPC assembly.