Sabine Schneider

This study investigates how synthetic 5' cap analogues interact with eIF4E, revealing structural features that influence mRNA translation efficiency and biological activity.

The paper benchmarks cross-platform RNA modification quantification using LC-MS/MS and finds that harmonized workflows and SILIS normalization improve reproducibility across different instrument types.

This study assesses ALKBH1 activity in vitro and in human cell lines using mass spectrometry, finding no significant impact on tRNA modifications under optimal conditions.

This study shows that inositol hexakisphosphate (IP6) is an essential cofactor for ADAR1 activity, with its depletion reducing RNA editing and supplementation restoring it.

This paper identifies two histidines in AdiY that act as pH sensors, triggering conformational changes that activate acid resistance genes in E. coli.