Eugene Serebryany

This study investigates how Cys depletion in γD-crystallin leads to misfolding and aggregation through dimerization, revealing a novel pathway for age-related cataract formation.

This study uses disulfide engineering to identify pro- and anti-aggregation conformers of human α-synuclein, revealing previously unknown polymorphs and their functional impacts.

This paper describes a method to produce cyclic peptides from natural or recombinant proteins without enzymes, enabling cost-effective and scalable synthesis of stable, biodegradable cyclic peptides.