Author

Xiang Wang

Denali Therapeutics (United States)ORCID 0000-0003-1090-5770Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Xiang Wang4 papers · Chinese Academy of Medical Sciences & Peking Union Medical College

Biology Disciplines

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Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

Maayan R. AgamiD· 2 shared Ahlam N. QerqeziD· 1 shared Anastasia G. HenryiD· 1 shared Ann Hong NguyeniD· 1 shared Annie ArguelloiD· 1 shared Anthony A. EstradaiD· 1 shared Benjamin J. HuffmaniD· 1 shared Brian M. Fox· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersNeuroscience

Maayan R. AgamORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintOct 6, 2025

CNS-penetrant NLRP3 inhibitor achieves durable weight loss and reverses hypothalamic inflammation in diet-induced obesity

Jing Guo, Tomás P. Bachor, Ryan Takahashi…·Ernie Yulyaningsih

TN-783, a CNS-penetrant NLRP3 inhibitor, induces sustained weight loss and reverses hypothalamic inflammation in diet-induced obese mice.

1 citation

mouseproteomics

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Cell BiologybioRxivPreprintAug 28, 2025

A Common PD-Risk GBA1 Variant Disrupts LIMP2 Interaction, Impairs Glucocerebrosidase Function, and Drives Lysosomal and Mitochondrial Dysfunction

Oliver B. Davis, Jennifer E. Kung, Sonnet S. Davis…·Anastasia G. Henry

This study shows the PD-risk GBA1 variant E326K reduces lysosomal GCase activity by disrupting LIMP2 interaction and causes lysosomal and mitochondrial dysfunction.

1 citation

humanproteomics

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