Author

Xianhe Li

University of California, Los AngelesORCID 0000-0003-1099-518XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:electronic health records· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Assay:metabolomics· 1

Frequent Co-Authors

Lena F. PernasiD· 2 shared Andrea MesarosiD· 1 shared Bruna Martins GarciaiD· 1 shared Irina RaisiD· 1 shared Jose M DelgadoiD· 1 shared Kira AllmerothiD· 1 shared Kit‐Yi LeungiD· 1 shared Martin Purrio· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersMicrobiology

Lena F. PernasORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintApr 24, 2026

Pathogen-induced formation of a nascent organelle derived from mitochondria

Xianhe Li, Jose M Delgado, Yubai Sun, Lena F. Pernas

This study shows that Toxoplasma gondii induces the formation of acidified mitochondrial-derived compartments called SPOTs to support parasite growth.

1 citation

humanelectronic health records

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Cell BiologybioRxivPreprintMay 7, 2025

Metabolic immunity to infection is driven by mitochondrial one-carbon metabolism

Tania Medeiros, Silvia Reato, Xianhe Li…·Lena F. Pernas

The paper shows ATF4 rewires mitochondrial one-carbon metabolism during infection to restrict Toxoplasma growth via folate competition.

DOI 10.1101/2025.05.07.652698

mousemetabolomics

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