Author

Alan Cochrane

University of TorontoORCID 0000-0002-8924-5682Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:metagenomics· 1 Assay:proteomics· 1

Frequent Co-Authors

Ali Zahedi AmiriiD· 1 shared Benoı̂t ChabotiD· 1 shared Beth Binnington· 1 shared Choudhary Ahmed· 1 shared Donald R. BranchiD· 1 shared Filomena Grosso· 1 shared Galicier Lionel· 1 shared Haomin Leng· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

Ali Zahedi AmiriORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

A cell line model for the study of CD4-negative HIV-1 infection and latent virus reservoirs

Galicier Lionel, Beth Binnington, Raymond Wong, Alan Cochrane, Jiazhen Jin, Donald R. Branch

This paper establishes a CD4-negative cell line model for studying HIV-1 infection and latent viral reservoirs, showing that CD4-negative cells can be infected and support both productive and latent infection.

bioRxiv · Jul 1, 2026 · PreprintPathology

Exploiting the Achilles' Heel of Viral RNA Processing to Develop Novel Antivirals

Ali Zahedi Amiri, Choudhary Ahmed, Subha Dahal, Filomena Grosso, Haomin Leng, Peter Stoilov, Maria Mangos, Johanne Toutant, Lulzim Shkreta, Liliana Attisano, Benoı̂t Chabot, Martha Brown, Mario Huesca, Alan Cochrane

This paper identifies 5342191 as a broad-spectrum antiviral that inhibits HIV-1, adenovirus, coronavirus, and influenza by altering viral RNA accumulation and structural protein expression.

Viruses · Dec 31, 2024Peer-reviewedMicrobiology