Author

Tianyan Gao

University of KentuckyORCID 0000-0003-1159-3625Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Chaohao LiiD· 1 shared Derek B. AllisoniD· 1 shared Emilia GalperiniD· 1 shared Fengyi MaoiD· 1 shared Jia PengiD· 1 shared Jinghui LiuiD· 1 shared Lina G. Abdelmoti· 1 shared Patricia G. Wilson· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Chaohao LiORCID

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2 papers

Recent·Most cited

Cancer BiologyJournal of Biological ChemistryPeer-reviewedJun 20, 2025

Dysregulation of mitochondrial function by PLK1-mediated PDHA1 phosphorylation promotes Cr(VI)-associated lung cancer progression

Qiongsi Zhang, Jia Peng, Zhiguo Li…·Xiaoqi Liu

This study shows that PLK1-mediated PDHA1 phosphorylation impairs mitochondrial function and promotes Cr(VI)-induced lung cancer progression by disrupting energy metabolism and apoptosis.

6 citations

humanbulk RNA-seq

𝕏 PostBluesky

BiochemistryHuman Molecular GeneticsPeer-reviewedJun 10, 2024

The expression of congenital Shoc2 variants induces AKT-dependent feedback activation of the ERK1/2 pathway

Patricia G. Wilson, Lina G. Abdelmoti, Tianyan Gao, Emilia Galperin

This study shows that Shoc2 variants associated with NSLH alter ERK1/2 phosphorylation levels depending on AKT pathway activation, revealing a feedback mechanism in EGFR signaling.

1 citation

humanexperimental assay

𝕏 PostBluesky