Quantification of lipid sorting during clathrin-mediated endocytosis
H. Mathilda Lennartz, Susana da Costa Nunes, Kristin Böhlig, Aditya Chhatre, Radek Šachl, Sascha M. Kuhn, Lior Moneta, Pavel Barahtjan, Wan Yee Yau, Juan Manuel Iglesias‐Artola, Martin Hof, Lukáš Opálka, Carl D. Modes, Alf Honigmann, André Nadler
This study quantifies lipid sorting during clathrin-mediated endocytosis and finds that lipid asymmetry in the plasma membrane explains observed partitioning, with minimal selectivity for cytoplasmic leaflet lipids compared to non-vesicular trafficking.
Nature Cell Biology · Sep 29, 2026Peer-reviewedCell Biology