Naël Osmani

This study uses 3D invasion models of RCC cell lines to predict their metastatic potential in vivo, showing that 3D models better reflect in vivo behavior than 2D assays.

This study shows that tumor cell viscosity affects their ability to circulate and extravasate, influencing metastasis.

This study identifies endothelial calcium signaling as a key driver of tumor cell extravasation through mechanistic and imaging analyses in zebrafish embryos.

This paper identifies a three-dimensional extracellular matrix cage formed by laminin and collagen IV that anchors megakaryocytes in the bone marrow and regulates their maturation and intravasation.