Salvatore Girardo

This study uses adipose-mimetic hydrogels to show that soft mechanical cues from adipocytes enhance breast cancer cell invasion by altering ECM structure and cellular confinement.

This study shows that tumor cell viscosity affects their ability to circulate and extravasate, influencing metastasis.

This study shows that flow conditions in droplet microfluidics significantly affect the elasticity and size of PAAm microgels, despite identical monomer concentrations.

This study shows cancer cells follow intrinsic self-organized programs that coordinate tumor cell state transitions during growth, revealing mechanical gradients and stereotyped patterns of heterogeneity and plasticity.

This study identifies endothelial calcium signaling as a key driver of tumor cell extravasation through mechanistic and imaging analyses in zebrafish embryos.