Daniel Andergassen

The paper develops Allelome.LINK to predict cis-acting ncRNA-targets using allele-specific expression, finding 2,291 shared events validated by eQTLs and linking 30.59% of GWAS variants to pcGene targets.

This study investigates epigenetic mechanisms in mammals, revealing distinct roles of DNA methylation and Polycomb group repressors in autosomal imprinting and identifying unique pathways in the extraembryonic ectoderm.

The paper measures cis and trans effects on regulatory elements between human and mouse to show cis-trans compensation is uncommon within individual elements.

This study shows that Firre and Dxz4 deletions in mice affect autosomal gene regulation without impacting XCI.