Author

Emily J. Illingworth

Johns Hopkins UniversityORCID 0000-0003-1224-2990Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Pharmacology & Toxicology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Assay:metabolomics· 1

Frequent Co-Authors

Aakriti MathuriD· 2 shared André KleensangiD· 2 shared Fenna C.M. SilléiD· 2 shared Kristal A. RychlikiD· 2 shared Sylvia S. SancheziD· 2 shared Alexandra MaertensiD· 1 shared Brian Leei LiniD· 1 shared Chloe M. KashiwagiiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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2 shared papersPharmacology & Toxicology

Aakriti MathurORCID

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3 papers

Recent·Most cited

Pharmacology & ToxicologyToxicologyPeer-reviewedFeb 10, 2026

Prenatal Arsenic Exposure and Gene Expression in Fetal Liver, Heart, Lung, and Placenta

Kristal A. Rychlik, Sylvia S. Sanchez, Chloe M. Kashiwagi…·Fenna C.M. Sillé

This study examines gene expression changes in fetal liver, heart, lung, and placenta after prenatal arsenic exposure in mice, identifying immune-related pathway alterations and reduced Gbp3 expression in female placentas.

DOI 10.1016/j.tox.2026.154420

mousebulk RNA-seq

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ImmunologybioRxivPreprintJul 14, 2025

Developmental Immunotoxicity of Low-dose Inorganic Arsenic Reprograms Macrophages Inducing Tumor-promoting Phenotypes

Emily J. Illingworth, Sylvia S. Sanchez, Kristal A. Rychlik…·Fenna C.M. Sillé

This study shows that low-dose inorganic arsenic exposure reprograms macrophage polarization, increasing tumor-promoting activity and altering immune responses in a sex-dependent manner.

DOI 10.1101/2025.07.14.663593

mouseproteomics

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Pharmacology & ToxicologyAmerican Journal of Physiology-Heart and Circulatory PhysiologyPeer-reviewedJan 31, 2025

Gestational arsenite exposure alters maternal postpartum heart size and induces Ca2+ handling dysregulation in cardiomyocytes

Nicole Taube, Morgan Steiner, Obialunanma V. Ebenebe…·Mark Jeffrey Kohr

This study shows that gestational arsenic exposure increases postpartum heart size and disrupts calcium handling in cardiomyocytes.

2 citations

mouseproteomics

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