Nicole F. Liachko

This study identifies tubulin gene mutations that rescue tauopathy phenotypes in C. elegans by altering microtubule properties rather than directly affecting tau protein levels or aggregation.

This study identifies TMEM106B C-terminal fragments as aggregating proteins linked to neurodegenerative diseases and shows their toxic effects in a C. elegans model.

This study identifies CYP and EH metabolites involved in Aβ and tau-induced neurodegeneration in C. elegans, showing that EH inhibition reduces neurodegeneration by altering the epoxy-to-hydroxy ratio of CYP-EH metabolites.