Synapse development is regulated by microglial THIK-1 K+ channels
Pablo Izquierdo, Hiroko Shiina, Chanawee Hirunpattarasilp…·David Attwell
This study shows that THIK-1 K+ channels in microglia regulate phagocytosis and synaptic pruning, with loss of THIK-1 increasing synaptic density in the hippocampus.