Anusha Mishra

This study shows that stroke and Alzheimer's disease independently affect neurovascular function but together increase amyloid deposition in Tg2576 mice.

This study uses chemogenetic activation of pericytes in mice to show their ability to contract capillaries and cause hypoperfusion, particularly in limbic regions.

This study investigates the role of astrocyte gap junctions and Kir channels in K+ buffering and neuronal excitability by blocking these mechanisms in cortical slices.

The paper introduces a novel mouse model of mild subcortical stroke and shows that astrogliosis spreads widely and independently of microglia and age.

This study shows that remyelination protects neurons from DLK-mediated neurodegeneration by preventing apoptosis and inflammation in a mouse model of demyelination.

This study identifies 20-HETE-dependent vasoconstriction as a mechanism impairing neurovascular coupling after stroke, showing that inhibiting its synthesis can restore blood flow in peri-infarct regions.

The paper introduces sciMAP-ATAC, a method for spatially resolved single-cell chromatin accessibility profiling, and applies it to study cortical lamination, spatial trajectories, and ischemic infarct progression in mouse and human tissues.

This study shows that amyloid β oligomers constrict human capillaries via pericyte signaling, reducing blood flow and contributing to Alzheimer’s disease pathology.