Author

Greg James

Great Ormond Street HospitalORCID 0000-0003-3014-7428Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Chanawee HirunpattarasilpiD· 1 shared David AttwelliD· 1 shared Felipe Santos Simões de FreitasiD· 1 shared Huma SethiiD· 1 shared Jiandong HuoiD· 1 shared Josef T. KittleriD· 1 shared Raymond J. OwensiD· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Chanawee HirunpattarasilpORCID

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1 paper

Recent·Most cited

NeurosciencebioRxivPreprintApr 1, 2021

SARS-CoV-2 binding to ACE2 triggers pericyte-mediated angiotensin-evoked cerebral capillary constriction

Chanawee Hirunpattarasilp, Greg James, Felipe Santos Simões de Freitas…·David Attwell

This study shows SARS-CoV-2 binding to ACE2 on pericytes enhances angiotensin II-induced cerebral capillary constriction via AT1 receptors, suggesting AT1 blockers may mitigate brain blood flow reduction in infection.

15 citations

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