Ananda Sanches-Medeiros

The paper shows that the ParB-CTPase fold can be repurposed as an ATPase toxin in bacterial contact-dependent growth inhibition systems, with toxic effects in both plant and animal cells.

The paper develops FRET-based c-di-GMP biosensors and applies them with FRET-To-Sort to map regulatory networks controlling c-di-GMP levels in E. coli.

The paper constructs synthetic promoters in E. coli to study how cis-regulatory element arrangements affect transcription factor binding and gene expression outcomes.

This paper identifies novel broad host-range transcriptional terminators from metagenomic data for use in Proteobacteria.

The paper identifies an amino acid critical for inducer recognition in bacterial regulators and creates engineered TFs responsive to aspirin.