Tung B. K. Le

This paper shows TrbA interacts with KorB to lock it as a transcriptional repressor on multi-drug resistance plasmids, using a conserved aromatic interface.

The paper investigates dual ParABS partition systems in Streptomyces plasmid SCP1, showing that while both systems are functional, only parABS1 is essential for plasmid maintenance.

The paper shows that the ParB-CTPase fold can be repurposed as an ATPase toxin in bacterial contact-dependent growth inhibition systems, with toxic effects in both plant and animal cells.

The paper identifies the ParB-CTPase fold as a versatile NTP-binding module found across diverse organisms, showing expanded nucleotide specificity and functional diversity through domain fusions.

This study maps transcriptional activity and chromosome architecture in Bdellovibrio bacteriovorus across its predatory lifecycle stages using multi-omics approaches.

This study identifies SegA and SegB as key proteins linking chromosome organization to genome segregation in archaea, showing their role in chromosome condensation and partitioning.

This study identifies a CTP-independent ParABS system in Streptomyces coelicolor that segregates plasmid SCP2 through a ParT protein that diffuses on DNA without CTP binding or hydrolysis.

This study identifies a bacterial immune system, LypABC, that controls GTA release in Caulobacter crescentus by coupling GTA activation with host cell lysis.

The paper shows that KorB, a DNA-sliding clamp, switches to a repressor role with KorA to mediate long-range gene silencing on plasmid RK2.

The paper investigates how GafY and GafZ regulate the CcGTA gene cluster in Caulobacter crescentus through transcriptional activation and anti-termination mechanisms.

The paper identifies a conserved bacterial transcription factor, Cada2, that mediates a methylation-dependent DNA damage response distinct from the SOS response.