Author

Lauren M. Sloat

Brigham and Women's HospitalORCID 0000-0003-1315-1302Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Adam NelsoniD· 1 shared Alexander WoglariD· 1 shared Anne M. VilleneuveiD· 1 shared Arielle Lutterman HeekeiD· 1 shared Candace Bavette MainoriD· 1 shared Claudine J. IsaacsiD· 1 shared Cristina Piñeiro LópeziD· 1 shared Edward T. RichardsoniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

Adam NelsonORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintSep 18, 2026

TALAVE in Breast Cancer: BRCA1/2 Mutation-Dependent Immune Remodeling after PARP Inhibition with Limited Checkpoint Engagement

Filipa C. Lynce, Kaoru Shimada, Claudine J. Isaacs…·Jennifer L. Guerriero

The paper shows BRCA-mutant breast cancers respond to PARP inhibitors with immune remodeling, but PD-L1 blockade is ineffective due to spatial separation of PD-L1+ cells and PD-1+ T cells.

DOI 10.64898/2026.09.17.752386

humanbulk RNA-seq

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Cell BiologybioRxivPreprintNov 12, 2025

Multi-step implementation of meiotic crossover patterning

Ivana Čavka, Alexander Woglar, Yule Wu…·Simone Köhler

The paper investigates the timing and mechanism of crossover designation in C. elegans using advanced imaging techniques, revealing a multi-step, dynamic regulation process.

3 citations

C. elegansimaging

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