Heather Eckart

Single-cell genomics improves the discovery of risk variants and genes of Atrial Fibrillation

This study integrates single-cell epigenomics with GWAS to identify risk variants and genes for Atrial Fibrillation, highlighting key transcription factors and pathways.

A molecular atlas of the human postmenopausal fallopian tube and ovary from single-cell RNA and ATAC sequencing

This study generates single-cell RNA and ATAC sequencing data from postmenopausal human fallopian tubes and ovaries, revealing distinct cell types and regulatory landscapes with implications for gynecologic diseases.

Hedgehog signaling activates a heterochronic gene regulatory network to control differentiation timing across lineages

This study identifies Hedgehog signaling as a regulator of differentiation timing through a heterochronic gene regulatory network in cardiac and neural lineages.

mDrop-seq: Massively parallel single-cell RNA-seq of Saccharomyces cerevisiae and Candida albicans

The paper introduces mDrop-seq, a high-throughput scRNA-seq technique for yeast species, and demonstrates its use in profiling gene expression in Saccharomyces cerevisiae and Candida albicans under various conditions.

A Hedgehog-FGF signaling axis patterns anterior mesoderm during gastrulation

This study identifies a Hedgehog-FGF signaling axis critical for anterior mesoderm patterning during gastrulation using single-cell transcriptomics in Hh-deficient embryos.

Systematic Comparison of High-throughput Single-Cell and Single-Nucleus Transcriptomes during Cardiomyocyte Differentiation

The paper compares Drop-seq and DroNc-seq in profiling cardiomyocyte differentiation, finding similar cell types and trajectories in both methods.