Author

Annika Wagener

Heidelberg University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

André FisahniD· 1 shared Bernd SchröderiD· 1 shared Brigitte NuscheriD· 1 shared Caterina Grassi· 1 shared Caterina Travisan· 1 shared Federico PicciauiD· 1 shared Gefei CheniD· 1 shared Ibrahim BoussaadiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperNeuroscience

André FisahnORCID

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2 papers

Recent·Most cited

Loss of the Parkinson's disease-associated protein DJ-1 impacts dopamine metabolism in astrocytes

Annika Wagener, Naiyareen Fareeza Mayeen, Stephan A. Müller, Sarah K. Tschirner, Brigitte Nuscher, Pauline Mencke, Stefan F. Lichtenthaler, Ibrahim Boussaad, Rejko Krüger, Lena F. Burbulla

This study shows that DJ-1 mutations impair astrocytic dopamine metabolism, leading to disrupted detoxification and potential contribution to Parkinson's disease pathogenesis.

bioRxiv · Nov 2, 2025 · PreprintNeuroscience

Signal Peptide Peptidase-Like 2b affects APP cleavage and exhibits a biphasic Aβ-mediated expression in Alzheimer's disease.

Riccardo Maccioni, Caterina Travisan, Stefania Zerial, Annika Wagener, Yuniesky Andrade‐Talavera, Federico Picciau, Caterina Grassi, Gefei Chen, Laëtitia Lemoine, André Fisahn, Richeng Jiang, Regina Fluhrer, Torben Mentrup, Bernd Schröder, Per Nilsson, Simone Tambaro

This study shows that SPPL2b affects APP cleavage and has biphasic Aβ-mediated expression in Alzheimer's disease, suggesting it as a potential drug target.

bioRxiv · Oct 24, 2022 · PreprintNeuroscience