Author

Sheng Yao

Chinese Academy of SciencesORCID 0000-0003-1402-4153Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:protein structure· 1 Organism:virus· 1

Frequent Co-Authors

Chang‐Qiang Ke· 1 shared Fang BaiiD· 1 shared Haixia SuiD· 1 shared Hang XieiD· 1 shared Hong Shu LiuiD· 1 shared Hualiang JiangiD· 1 shared Jia LiuiD· 1 shared Jianping ZuoiD· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Chang‐Qiang Ke

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1 paper

Recent·Most cited

Molecular BiologybioRxivPreprintApr 13, 2020

✦ In-depth digest

Discovery of baicalin and baicalein as novel, natural product inhibitors of SARS-CoV-2 3CL protease in vitro

Haixia Su, Sheng Yao, Wenfeng Zhao…·Yechun Xu

Baicalin and baicalein from Scutellaria baicalensis inhibit SARS-CoV-2 3CL protease non-covalently; a 2.2 Å baicalein complex structure shows an unusual shield-like binding mode.

143 citations

virusprotein structure

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