Author

Daniel Ivanov

Brown UniversityORCID 0000-0003-1419-6270Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1 Assay:proteomics· 1

Frequent Co-Authors

Christopher J. BakkenistiD· 2 shared Frank P. VendettiiD· 2 shared Katherine M. AirdiD· 2 shared Pinakin PandyaiD· 2 shared Raquel BujiD· 2 shared Reyna Jones· 2 shared Robert William SoboliD· 2 shared Sudipta PathakiD· 2 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersCancer Biology

Christopher J. BakkenistORCID

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2 papers

Recent·Most cited

Cancer BiologyNAR CancerPeer-reviewedOct 7, 2025

Uracil-DNA glycosylase deficiency is associated with repressed tumor cell-intrinsic inflammatory signaling and altered sensitivity to exogenous interferons

Frank P. Vendetti, Pinakin Pandya, Carina R. Sclafani…·Christopher J. Bakkenist

This study shows that UNG deficiency in tumor cells reduces intrinsic inflammatory signaling and alters interferon sensitivity, leading to a modified tumor microenvironment.

2 citations

mousebulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintApr 4, 2024

Deoxyuridine-rich cytoplasmic DNA antagonizes STING-dependent innate immune responses and sensitizes resistant tumors to anti-PD-L1 therapy

Pinakin Pandya, Frank P. Vendetti, Joseph El-Ghoubaira…·Christopher J. Bakkenist

The paper shows that dU-rich cytoplasmic DNA inhibits STING-dependent immune responses and enhances anti-PD-L1 therapy efficacy in tumors.

2 citations

mouseDNA methylation

𝕏 PostBluesky