Ting Zhou

The paper maps bird sound activity in Shenzhen using AI and acoustic monitoring to inform urban planning and monitoring priorities.

Open-source STAR binary for five transcriptomic assays runs 3.9- to 6.2-fold faster than Cell Ranger 9.0.1 for scRNA-seq and Perturb-seq, 17- to 41-fold for Flex, with closely concordant counts.

The paper identifies a mesodermal progenitor in mouse gastrula and human iPSC cultures that gives rise to pro-definitive angio-hematopoietic lineage cells, including yolk sac endothelium, blood islands, and macrophages.

This study investigates itaconate's role in human macrophages, showing distinct effects in alveolar-like and M-CSF-derived macrophages during M. tuberculosis infection.

This study develops a CRISPRa-based method to rapidly verify gene editing in human pluripotent stem cells without differentiation.

The paper identifies microglia-specific somatic clones with pathogenic variants in Alzheimer's Disease patients that drive neuro-inflammation through the MAPK pathway.

This paper develops an inducible prime editing system in human pluripotent stem cells that enables efficient and controllable multiplex genome editing.

This study identifies RXR signaling as a mediator of lipid metabolism in leptomeningeal metastatic cancer cells, revealing a potential therapeutic target.

This study generates human cerebral organoids with a structured outer subventricular zone by activating the STAT3 pathway with LIF, mimicking in vivo oRG development and enhancing neuronal maturation.

This study functionally interrogates 20 T2D-associated genes using isogenic hESC-derived β-like cells, identifying variants and genes linked to insulin production and lipotoxicity sensitivity.