Guy R Oldrieve

This paper presents a telomere-telomere genome assembly of Trypanosoma congolense, revealing distinct VSG organization and expression mechanisms compared to Trypanosoma brucei.

This study shows that Trypanosoma congolense expresses multiple Variant Surface Glycoprotein genes in single cells, unlike Trypanosoma brucei, which uses monoallelic transcription.

The paper analyzes antigenic variation in Trypanosoma brucei during chronic bovine infections, revealing enhanced diversity and a reproducible temporal expression hierarchy of VSGs.

vsgseq2 improves the analysis of VSG expression diversity and abundance in Trypanosoma brucei populations using updated bioinformatics tools.

The paper investigates the evolutionary history of Wolbachia symbiosis in filarial nematodes by analyzing nuclear Wolbachia transfers and genome sequences, revealing complex patterns of cospeciation, loss, and replacement.

This study identifies molecular changes and reversible steps in the loss of stumpy transmission in monomorphic trypanosomes using genomic analysis and laboratory selection.

This paper sequences and compares the genomes of two non-pathogenic trypanosomes to identify genomic features associated with host and vector specificity.

The paper re-analyzes genomic data to define clades of monomorphic Trypanozoon species and identifies lineage-specific variation, challenging traditional classifications and suggesting evolutionary relationships.