Andrew P. Jackson

An improved Trypanosoma vivax genome assembly confirms the distinct organisation of its variant antigen repertoire

The paper presents an improved T. vivax genome assembly, revealing distinct VSG gene organization and expression mechanisms compared to T. brucei.

Trypanosoma congolense Variant Surface Glycoprotein gene expression occurs in the absence of monoallelic transcription control

This study shows that Trypanosoma congolense expresses multiple Variant Surface Glycoprotein genes in single cells, unlike Trypanosoma brucei, which uses monoallelic transcription.

Restricted expression site use and extreme genome diversification drives trypanosome antigenic variation in chronic bovine infections

The paper analyzes antigenic variation in Trypanosoma brucei during chronic bovine infections, revealing enhanced diversity and a reproducible temporal expression hierarchy of VSGs.

Essential function reflected in the phylodynamics of a multigene family: the pir genes of malaria parasites

This study investigates the evolutionary dynamics and essential function of pir genes in malaria parasites, identifying pirC1 as critical for blood stage growth and suggesting a role in host cell interaction or nutrient uptake.

Development of antisense tools to study Bodo saltans and its intracellular symbiont

This study attempts to use antisense inhibition to analyze gene function in an obligate symbiosis but concludes it is not feasible due to holobiont growth in response to antisense treatment.

VAPPER: High-throughput Variant Antigen Profiling in African trypanosomes

VAPPER enables high-throughput analysis of variant antigen repertoires in African trypanosomes, providing profiles and comparisons with existing strains.