Apollo 3: Multi-Species Genome Curation
Garrett Stevens, Kyösti Sutinen, Dario Beraldi…·Ian H Holmes
Apollo 3 is a new manual genome annotation tool that integrates with JBrowse 2, enabling multi-genome editing and synteny visualization.
Author
University of GlasgowORCID 0000-0003-1504-5212Unclaimed ORCID profile · follow to get notified of new preprints
7 papers
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Garrett Stevens, Kyösti Sutinen, Dario Beraldi…·Ian H Holmes
Apollo 3 is a new manual genome annotation tool that integrates with JBrowse 2, enabling multi-genome editing and synteny visualization.
Marija Krasiļņikova, Jane C. Munday, Dario Beraldi…·Richard McCulloch
This paper presents a telomere-telomere genome assembly of Trypanosoma congolense, revealing distinct VSG organization and expression mechanisms compared to Trypanosoma brucei.
Joao da Silva Filho, Elamaran Meibalan, Himanshu Gupta…·Matthias Marti
This study shows that severe malarial anaemia is linked to increased red blood cell production, iron metabolism, tissue injury, and parasite biomass in bone marrow, with better resolution from bone marrow analysis than peripheral blood.
Omar Janha, Niniola Olaniyan, Ka Diam Go…·Katarzyna Modrzynska
This study shows that inhibiting PfCLK3 disrupts RNA-splicing in malaria parasites, affecting 1125 genes and providing a novel mechanism for a radical cure.
Jeziel D. Damasceno, Gabriel L. A. Silva, Catarina A. Marques…·Richard McCulloch
Marija Krasiļņikova, Catarina A. Marques, Emma M. Briggs…·Richard McCulloch
This study uses Nanopore sequencing to show that DNA replication compartmentalization in Trypanosoma brucei affects genome stability and instability by influencing VSG gene recombination and chromosome stability.
Eun‐Ang Raiber, Guillem Portella, Sergio Martínez Cuesta…·Shankar Balasubramanian
This study shows that 5-formylcytosine (5fC) influences nucleosome positioning through covalent histone-DNA interactions in mouse embryonic stem cells.