Vojtěch Kumpošt

This study uses single-cell transplantation and mathematical modeling to show that lineage biases in hematopoiesis arise from extrinsic feedback and clonal competition, not intrinsic HSC properties.

The paper shows that noise improves synchronization of a population of oscillators to external signals by increasing sensitivity and speeding up adjustment to phase changes.

The paper develops a stochastic oscillator model to simulate how light entrains zebrafish circadian clocks and applies it to predict effects of pharmacological treatments on entrainment dynamics.