Author
University College CorkORCID 0000-0003-1451-9105Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Xueyan Li, Philipp Konrad Zuber, Gary Loughran…·John F. Atkins
The paper investigates the StopGo/2A translational recoding mechanism using cryo-EM and bioinformatics, revealing structural and sequence features that enable this process in viruses.
Simon A. Fromm, Kate M. O’Connor, Michael D. Purdy…·Simone Mattei
The paper determines the structure of the translating bacterial ribosome at 1.55 Å resolution using open access cryo-EM, enabling detailed analysis of ribosome polymorphism and drug design.
Pramod R. Bhatt, Alain Scaiola, Gary Loughran…·Nenad Ban
This study presents the cryo-EM structure of the mammalian ribosome during SARS-CoV-2 RNA translation, revealing the pseudoknot structure that facilitates ribosomal frameshifting and identifies a compound that inhibits viral replication.