Kyle J. Roux

This study identifies ATP2B1 as a regulator of Norrin- and WNT7A/B-induced Frizzled4 signaling in endothelial cells, showing its role in CNS vascular development.

This study identifies MARCHF8 as a driver of cancer immune evasion by degrading MHC-I proteins and shows its inhibition enhances antitumor immunity and response to immunotherapy.

This study shows that different sterols affect DVL2 localization and function through specific structural interactions, impacting cell signaling and homeostasis.

This study identifies a shared protein network involving Batten disease proteins that regulates synaptic composition and function through interactions with vesicle sorting proteins.

This study maps the SARS-CoV-2 virus-host interactome using BioID in A549 cells and provides a public resource for analyzing host-viral protein associations.