Author

Colin R. Detrick

Stanford MedicineORCID 0009-0002-4115-1668Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:mouse· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Dmitri A. PetroviD· 3 shared Jess D. HebertiD· 3 shared Laura AndrejkaiD· 3 shared Monte M. WinslowiD· 3 shared Saswati KarmakariD· 3 shared Yuning J. TangiD· 3 shared Christian A. KunderiD· 2 shared Emily G. ShuldineriD· 2 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCancer Biology

Dmitri A. PetrovORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Aging represses lung tumorigenesis and alters tumor suppression

Emily G. Shuldiner, Saswati Karmakar, Min K. Tsai, Jess D. Hebert, Yuning J. Tang, Laura Andrejka, Maggie R. Robertson, Minwei Wang, Colin R. Detrick, Hongchen Cai, Rui Tang, Christian A. Kunder, David M. Feldser, Dmitri A. Petrov, Monte M. Winslow

This study shows aging suppresses lung tumor initiation and growth in mice, with age-dependent effects on tumor suppressor genes like PTEN and persistent age-related transcriptomic changes in tumors.

Nature Aging · Nov 4, 2025Peer-reviewedCancer Biology

Functional mapping of epigenetic regulators uncovers coordinated tumor suppression by the HBO1 and MLL1 complexes

Yuning J. Tang, Haiqing Xu, Nicholas W. Hughes, Paloma A. Ruiz, Samuel H. Kim, Emily G. Shuldiner, Steven S. Lopez, Jess D. Hebert, Saswati Karmakar, Laura Andrejka, Deniz Nesli Dolcen, Gábor Zoltán Boross, Pauline Chu, Christian A. Kunder, Colin R. Detrick, , Monte M. Winslow

The paper identifies HBO1 and MLL1 complexes as key tumor suppressors in lung cancer using in vivo functional screens of epigenetic regulators.

Cancer Discovery · Sep 25, 2025Peer-reviewedCancer Biology

Efficient and multiplexed somatic genome editing with Cas12a mice

Jess D. Hebert, Haiqing Xu, Yuning J. Tang, Paloma A. Ruiz, Colin R. Detrick, Jing Wang, Nicholas W. Hughes, Oscar Donosa, Vicky P. Siah, Laura Andrejka, Saswati Karmakar, Irenosen Aboiralor, Rui Tang, Rocío Sotillo, Julien Sage, , Monte M. Winslow

This study develops transgenic Cas12a mice to enable efficient, multiplexed somatic genome editing for studying complex genetic interactions in vivo.

Nature Biomedical Engineering · May 30, 2025Peer-reviewedCancer Biology