Motoyoshi Nagai

This study shows that breast cancer cells induce B cell loss in bone marrow, promoting bone metastasis, and that G-CSF mediates this effect, suggesting B cells and G-CSF as therapeutic targets.

This study shows a ketogenic diet reprograms host and microbiome functions to enhance tissue regeneration through IL-17A activation and microbial riboflavin and sphingomyelinase pathways.

This study shows that sulfide is essential for gut microbial and immune homeostasis, with its depletion causing immune dysfunction and impaired vaccine response.

This study identifies a neuroimmune CGRP-RAMP1 axis that modulates cutaneous adaptive immunity to the microbiota by constraining Type 17 responses and limiting T cell activation.