Claudia A. Rivera

This study shows that breast cancer cells induce B cell loss in bone marrow, promoting bone metastasis, and that G-CSF mediates this effect, suggesting B cells and G-CSF as therapeutic targets.

This study identifies a dominant population of IL-10-producing, T-bet-expressing CD4+ Tr1 cells in the small intestine that are shaped by dietary antigens rather than the microbiota.

This study shows that endogenous retroelements promote tolerance to dietary antigens by regulating regulatory T cell function and dendritic cell activity through innate sensing pathways.

The paper identifies a cholesterol metabolite that spatially organizes TH2 cells during fungal-induced pulmonary inflammation, promoting fungal persistence and suppressing interferon-gamma responses.

The paper shows that mild detergent exposure reactivates retroelements, inducing CD8+ T cells that enhance skin wound repair through IL-17A.

This study shows that forcing dimerization between ATF6f and XBP1s enhances UPR activity, reducing protein aggregation in neurodegenerative disease models.