Chih‐Hang Wu

The paper investigates the evolution of NRC helper NLRs across Solanaceae, identifying conserved core and dynamic periphery subfamilies and their functional rewiring.

This study shows how a plant pathogen effector blocks the stepwise assembly of a helper NLR resistosome by stabilizing an intermediate state.

This study identifies NRG1 as a plant NLR receptor that targets chloroplasts to trigger immunity by channeling stromal calcium into the cytosol, revealing a novel mechanism for organelle-specific immune signaling.

The study identifies a hydrophobic core in the coiled-coil domain of NRCs that is essential for their function in immunity.

This study enhances Agrobacterium-mediated genome editing in Arabidopsis by optimizing floral stages and engineering Agrobacterium to evade plant immunity, achieving high transformation efficiency without antibiotic selection.

The study shows that autoactive mutants of tomato NRC proteins still induce cell death in prf mutants and in lettuce, indicating a unidirectional dependency in the NRC immune network.

This paper compares transcriptomic responses of Agrobacterium strains under in vitro and in planta conditions, revealing strain-specific and context-dependent gene regulation during plant colonization.

BaMV infection enhances mitochondrial metabolism to regulate cytoplasmic redox balance and promote antiviral defense.

The paper visualizes calcium signaling and organelle dynamics during resistosome-mediated cell death in plants, revealing a sequential cascade of subcellular events.

This paper shows that Rhizobium rhizogenes A4-derived strains provide more efficient transient gene expression in Nicotiana benthamiana and other solanaceous plants compared to common agrobacterial strains.

This paper develops a copper-inducible gene expression system in Nicotiana benthamiana to tightly regulate transgene expression and cell death assays.