Author

Carlota Pereda Serras

University of California, San FranciscoORCID 0000-0003-1625-215XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2 Neuroscience· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Assay:scRNA-seq· 3 Assay:bulk RNA-seq· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2

Frequent Co-Authors

Marina SirotaiD· 3 shared Tomiko OskotskyiD· 3 shared Boris OskotskyiD· 2 shared Jessica R. BlumenfeldiD· 2 shared Seo Yeon YooniD· 2 shared Xinyu TangiD· 2 shared Yadong HuangiD· 2 shared Yanxia Hao· 2 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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3 shared papersBioinformatics

Marina SirotaORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

BioinformaticsbioRxivPreprintJul 22, 2026

Integrating single-cell and bulk transcriptomic perturbation resources reveals complementary therapeutic spaces for drug repurposing

Enock Niyonkuru, Umair Khan, Xinyu Tang…·Marina Sirota

CDRPipe integrates single-cell and bulk transcriptomic perturbation data to improve drug repurposing predictions by combining complementary resources.

DOI 10.64898/2026.07.17.739227

humanbulk RNA-seq

𝕏 PostBluesky

Neurosciencenpj DementiaPeer-reviewedApr 25, 2026

Multi-omic phenotyping of MAPT V337M neurons reveals early changes in axonogenesis and tau phosphorylation

Gregory A. Mohl, Gary Dixon, Emily Marzette…·Martin Kampmann

The paper uses multi-omic analysis to study MAPT V337M neurons, finding altered axonogenesis and tau phosphorylation, with p38 MAPK pathway involvement in tau phosphorylation in V337M neurons.

4 citationstop 1%

humanscRNA-seq

𝕏 PostBluesky

BioinformaticsbioRxivPreprintDec 8, 2025

Tri-AD: Hippocampal cell-type-specific responses to age, sex and APOE genotype

Yaqiao Li, Yanxia Hao, Carlota Pereda Serras…·Marina Sirota

The paper investigates how age, sex, and APOE genotype affect hippocampal cell-type-specific gene expression and communication in mice, revealing sex-divergent effects of APOE4.

DOI 10.64898/2025.12.03.691944

mousesnRNA-seq

𝕏 PostBluesky

Systems BiologybioRxivPreprintDec 9, 2024

Data-driven discovery of cell-type-directed network-correcting combination therapy for Alzheimer's disease

Yaqiao Li, Carlota Pereda Serras, Jessica R. Blumenfeld…·Marina Sirota

The paper identifies a cell-type-directed combination therapy for Alzheimer's disease using single-cell transcriptomics and drug databases, showing improved memory and reduced pathologies in a mouse model.

3 citations

mousescRNA-seq

𝕏 PostBluesky