Author

Jiangchuan Shen

Duke UniversityORCID 0000-0003-1699-564XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:metabolism & bioenergetics· 1 Organism:yeast· 1

Frequent Co-Authors

Giovanni González-GutiérreziD· 1 shared Hengyao NiuiD· 1 shared Quan WangiD· 1 shared Yuxi LiiD· 1 shared Zhitong Feng· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperBiochemistry

Giovanni González-GutiérrezORCID

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintSep 2, 2025

Dual DNA-binding capability of Cdc13 coordinates with Ku to safeguard telomere integrity

Zhitong Feng, Jiangchuan Shen, Yuxi Li…·Hengyao Niu

This study shows that Cdc13's dual DNA-binding capability coordinates with Ku to protect telomeres, and mutations in this function lead to metabolic reprogramming and increased fitness in yeast.

DOI 10.1101/2025.09.02.671137

yeastgenetic perturbation / CRISPR

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