Molecular BiologyNature Cell BiologyPeer-reviewed
LSM2-8 and XRN-2 contribute to the silencing of H3K27me3-marked genes through targeted RNA decay
Anna Mattout, Dimos Gaidatzis, Jan Padeken…·Susan M. Gasser
The paper identifies a pathway in C. elegans where LSM2-8 and XRN-2 selectively degrade H3K27me3-marked genes, revealing a new layer of heterochromatin regulation in animals.
31 citations