Dimos Gaidatzis

The paper shows that large transgene arrays in C. elegans cause transcriptional dysregulation and synthetic molting defects when combined with a myrf-1 mutation.

The paper identifies let-7 miRNA and lin-46 mRNA as the essential targets of LIN28 in C. elegans, showing they regulate developmental timing through coordinated control.

The paper develops a linear model to predict chromatin dynamics based on transcription factor binding in C. elegans, identifying key regulators that schedule gene expression rhythms.

The paper identifies BLMP-1 as a transcription factor that promotes oscillatory gene expression to regulate timely molting in C. elegans.

The paper identifies a pathway in C. elegans where LSM2-8 and XRN-2 selectively degrade H3K27me3-marked genes, revealing a new layer of heterochromatin regulation in animals.