Siddharth R. Krishnamurthy

The paper identifies a multi-kingdom microbial consortium that normalizes immune responses in laboratory mice, altering cancer outcomes and CAR T cell therapy responses.

This study shows that endogenous retroelements promote tolerance to dietary antigens by regulating regulatory T cell function and dendritic cell activity through innate sensing pathways.

The paper shows that mild detergent exposure reactivates retroelements, inducing CD8+ T cells that enhance skin wound repair through IL-17A.