Author

Offir Lupo

Weizmann Institute of ScienceORCID 0000-0003-1876-3527Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:yeast· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:protein sequence· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Naama BarkaiiD· 2 shared Avraham A. LevyiD· 1 shared Gat Krieger· 1 shared Gili Valinsky· 1 shared Sagie Brodsky· 1 shared Tamar Jana· 1 shared Vladimir MindeliD· 1 shared Wajd Manadre· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 24 mutual co-author links

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2 shared papersGenomics

Naama BarkaiORCID

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2 papers

Recent·Most cited

GenomicsbioRxivPreprintMar 5, 2025

Protein massively parallel binding assay reveals transcription factor binding determinants

Offir Lupo, Sagie Brodsky, Tamar Jana…·Naama Barkai

The paper introduces pMPBA, a method to analyze peptide-DNA binding in yeast, revealing determinants both within and outside predicted DNA binding domains.

1 citation

yeastprotein sequence

𝕏 PostBluesky

Systems BiologyGenome ResearchPeer-reviewedJul 1, 2020

Independent evolution of transcript abundance and gene regulatory dynamics

Gat Krieger, Offir Lupo, Avraham A. Levy, Naama Barkai

The paper profiles gene expression in related yeast species across hundreds of conditions to distinguish transcriptional regulation from expression level variation, finding that promoter strength changes drive divergence without altering network positioning.

13 citations

yeastbulk RNA-seq

𝕏 PostBluesky