Hana Yeh

This study shows that inhibiting CSF1R in male MIA offspring improves sociability and memory, while female offspring show no improvement, highlighting sex-specific therapeutic potential.

This study shows that atypical antipsychotics like clozapine and olanzapine alter microglial functions through astrocyte-derived extracellular vesicles by affecting phagocytosis and motility.

The paper screens CNS-penetrant compounds to identify small molecules that modulate microglial phagocytosis of synaptosomes, finding 28 compounds with significant effects.

This study shows that knocking out CYFIP1 in human microglia reduces synaptic vesicle phagocytosis, morphology changes, and motility, suggesting a role in synaptic pruning related to neurodevelopmental disorders.